The combination of two drugs showed encouraging results for patients suffering from advanced peritoneal mesothelioma.

The use of a checkpoint inhibitor along with a drug to slow the growth of new blood vessels may delay the progression of peritoneal mesothelioma as well as increase the life expectancy of patients diagnosed with the deadly disease caused by asbestos exposure.

A study by the University of Texas MD Anderson Cancer Center found that combining – atezolizumab (Tecentriq) plus bevacizumab (Avastin) – was safe and effective for peritoneal mesothelioma patients who were either intolerant to platinum-pemetrexed chemotherapy or saw the disease progress during prior treatment. The median time to next treatment increased from 8.3 months under platinum-pemetrexed chemotherapy to 17.6 months with atezolizumab/bevacizumab. One year after treatment, 61 percent of the peritoneal mesothelioma patients were progression free and 85 percent were still alive.

Malignant peritoneal is a rare and aggressive disease that is caused by on-the-job asbestos exposure, bystander or take-home exposure or the use of talcum powder. Because it is often not diagnosed until later stages, treating peritoneal mesothelioma is difficult. There are limited treatment options. Most often treatment includes a surgery to remove tumors along with chemotherapy to attempt to slow any progression. This recent study, which will need to be validated with larger clinical trials, suggests that more advanced treatments are on the horizon. That new hope presents a ray of light for peritoneal mesothelioma patients.

“Atezolizumab/bevacizumab was well tolerated and led to robust and durable responses in patients with malignant peritoneal mesothelioma who had progressed on, or were intolerant to, prior platinum-pemetrexed chemotherapy with meaningful prolongation of survival,” wrote the lead study author Kanwal P.S. Raghav, MBBS, MD, of The University of Texas MD Anderson Cancer Center. “This study establishes a promising treatment option for our patients who suffer from this morbid cancer and represents an unprecedented effort to bridge the gap of dedicated research in this … disease.”

The study was published on July 14, 2021 in the journal Cancer Discovery.

Peritoneal mesothelioma patients may wish to ask their oncologist about this new line of research and whether it is appropriate for their course of treatment.

RPWB has a 40-year history of helping people diagnosed with mesothelioma get compensation from asbestos manufacturers. We have recovered billions of dollars for our clients in their times of need. If you or a loved one is impacted by this disease, please give us a call to discuss your legal options.

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    How are Mesothelioma Lawsuits Paid Out?

    By Ken Wilson

    Some of the most frequent questions we get about mesothelioma lawsuits concern how they are ultimately paid out to clients and how long it will all take. To address those questions, let me give you a little bit of context about how mesothelioma lawsuits work.

    When a person is diagnosed with mesothelioma, asbestos lawyers like myself work with that client and other witnesses such as family members and co-workers to determine all of the places he/she has come into contact with asbestos. In addition to identifying the exposure locations, we also work using a variety of sources to identify all of the asbestos products used at those locations. From there, we can start to build a product liability case against all of the manufacturers of those products. The best mesothelioma lawyers can walk you through this process to make it as easy as possible.

    Most mesothelioma lawsuits involve a number of defendants that share culpability for causing the client’s mesothelioma. If the litigation is successful, the client will typically receive periodic settlement checks as various defendants settle. This includes both businesses in operation today and those that set aside money in bankruptcy trusts. This entire process can take several years from beginning to end, with most clients and their families beginning to receive money shortly after the case is commenced.

    Of course, it is important to note that every case is different and a good asbestos attorney will not rush through building the product liability case against the asbestos manufacturers.  A well developed, researched, and prepared case will increase the likelihood of a successful outcome.  Additionally, if a case goes to trial, the time frame for case resolution may be extended

    Over the past 33 years, I have dedicated my career to helping asbestos victims with mesothelioma lawsuits throughout the United States. To me and to the others in our firm, our clients are not a number; they are people who reach out to us for help at one of the most consequential and difficult times of their lives. My advice to people diagnosed with mesothelioma is to find the best medical and legal care that you can. Ask lots of questions and, if you feel uneasy, seek a second opinion. This will help you to enjoy time spent with family and friends.

    If I can ever be of assistance, feel free to contact me 1-866-594-8765 or send me an email.

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